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THE SMART
SYNBIOTIC

  • 200 billion CFU/g

  • Protected from stomach acid

  • Delivered directly to the intestines

WHEN DO I NEED PROCOMBO?

ABDOMINAL
DISCOMFORT

ANTIBIOTICS
INTAKE

REDUCED IMMUNE
PROTECTION

THERE IS A REVOLT
IN YOUR ABDOMEN?

DIARRHEA LAZY BOWEL
SYNDROME INTESTINAL
GAS STOMACH
GROWLING BLOATING FEELING OF
HEAVINESS
IN STOMACH

When you eat irregularly and your menu often includes fatty foods, fried foods and sweets, the stomach and intestines begin to resent. Even the slightest discomfort is a warning that an imbalance has occurred, and the abdominal activity is impaired. This also happens when we travel, when we change the environment, and when we take strong medication.

With ProCombo, your stomach functions calmly because it receives all the probiotic bacteria it needs on a daily basis.

YOU TAKE ANTIBIOTICS?

The purpose of an antibiotic is to kill the bacteria that make us sick. Along with them, however, it exterminates the population of the "good" bacteria as well, which disrupts the function of the intestines. Therefore, every third person treated with an antibiotic gets diarrhea.

ProCombo takes care of the health of your intestines when you are on strong medications because the "good" bacteria in it survive the hostile environment.

YOU ARE NOT AS HEALTHY AS YOU WANT TO BE?

Frequent illness indicates that your defenses are weakened. As much as 80% of the body's immune response is formed in the intestines. Therefore, impaired bowel function can make the entire body sick. Intestines also contain the so-called intestinal barrier that prevents the entry of harmful substances into the blood. Due to the large number of pathogens inhabiting the intestines, the highest concentrations of toxins are also to be found there.

ProCombo can protect you as it prevents "bad" bacteria from interfering with the immune system.

ARE YOU TAKING SOME PROBIOTIC, BUT IT'S NOT HELPING?

If you're already taking a probiotic but no improvement is to be seen, check if it meets all the standards for a functional probiotic product. A daily dose must contain at least 10 billion* live bacteria. It should also have a prebiotic to ensure the nutrition and development of the "good" bacteria, and be free of any sweeteners or flavorings. Even with only one checkbox not ticked, the desired effect may not be achieved.

You will feel the effect of ProCombo at the beginning of the intake, because it meets all the criteria for effectiveness.

*Benjamin Kligler (MD) & Andreas Cohrssen (MD). Probiotics. American Academy of Family Physicians (AAFP). 2008 Nov 1;78(9):1073-1078.)

WHAT MORE DOES
PROCOMBO DO?

Prebiotic Probiotic
La-14®

The Lactobacillus acidophilus strain in ProCombo is a patented probiotic under the name La-14®. It has undergone specialized studies that have proven his abilities. The unique properties of La-14® are not inherent to other L. acidophilus species. Chlorophyllin, which has been used in the new Green Capsule, contributes to the additional effects of ProCombo.

  • Improves digestion

  • Regulates peristalsis

  • Alleviates the symptoms of lactose intolerance

  • Helps in case of bacterial vaginosis and candidiasis

  • Supports the health of the mother and the baby of pregnant and nursing women

  • Controls the emission of body odors

  • Supports the breakdown of oxalates
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HOW DOES PROCOMBO WORK?

THE DUAL CAPSULE DOUBLES THE EFFECTIVENESS

ProCombo is produced with the use of the patented DUOCAP™ (capsule-in-capsule) technology. Thanks to its unique technological qualities, it has three key advantages:

  1. 1.  Targeted release
  2. 2.  Live probiotic bacteria
  3. 3.  1 capsule delivers everything that is necessary

All that leads to a significantly higher efficiency and visible results in the first days of the intake.

INTAKE
1.
The outer capsule dissolves in stomach and releases PREBIOTIC
2.
The inner capsule dissolves in intestines and delivers PROBIOTIC

WHAT ELSE SHOULD I KNOW ABOUT PROCOMBO?

HOW SHOULD IT BE TAKEN?

1 capsule per day, with a glass of water.

HOW LONG SHOULD IT BE TAKEN?

Between 10 days and 8 weeks, depending on the problem.

WHO IS IT SUITABLE FOR?

For persons over 12 years of age.

WHERE CAN I FIND IT?

Available on Amazon.

GLUTEN FREE
PRESERVATIVE
FREE
LACTOSE FREE

SUGAR FREE
GMO FREE

CURIOUS FACTS
Learn curious facts about ProCombo

RESEARCH
See what the research has shown

QUESTIONS AND ANSWERS
Frequently Asked Questions

AWARDS AND RECOGNITION
What awards has ProCombo been awarded with?
Product leaflet
Certificate of Analysis
PRODUCED BY CAPSUGEL FRANCE SAS – Capsugel Colmar, F-68027 Colmar, Cedex, France,
for VITASLIM INNOVE Ltd.; 128 City Road, London, EC1V 2NX
DUOCAP™ and LICAPS™ & logo are trademarks of Lonza or its affiliates
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SEND INQUIRY

*Required fields

The trademark ProCombo is owned by VITASLIM INNOVE Ltd.

PRODUCED BY CAPSUGEL FRANCE SAS – Capsugel Colmar, F-68027 Colmar, Cedex, France,
for VITASLIM INNOVE Ltd.; 128 City Road, London, EC1V 2NX; VAT 421 7977 78

SENT SUCCESSFULLY!

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CURIOUS FACTS

THE EXTRAORDINARY STRAIN LA-14®

ProCombo contains a special species of Lactobacillus acidophilus patented under the trade name La-14®. It is owned by the world leader in microbiology, DuPont®, and has many unique characteristics. The qualities of La-14® and its health effects cannot be attributed to other L. acidophilus species.

THE PREBIOTIC THAT FEEDS ONLY THE „GOOD“ BACTERIA

A prebiotic is any substance that bacteria recognize as their food. Most prebiotics, such as inulin, feed both „good“ and „bad“ bacteria. There are very few prebiotics that feed only the good bacteria. One of them is NutraFlora®, which is contained in ProCombo. It has been proven to support the growth and development of microorganisms of the Lactobacillus genus only, and Lactobacillus acidophilus (La-14®) has been added to ProCombo. NutraFlora® is a patented raw material that is derived from sugar cane. The producer is the multinational company Ingredion.

A SYNBIOTIC IS A LOT MORE THAN A PROBIOTIC

The synbiotic is a combination of a PRObiotic plus a PREbiotic. The two substances in have a synergetic action and mutually enhance their individual qualities. The effectiveness of the synbiotic corresponds to the formula 1 + 1 = 3. ProCombo is a synbiotic, as it contains the probiotic strain Lactobacillus acidophilus (La-14®) and the special prebiotic NutraFlora®.

THE DOUBLE CAPSULE IS A DOUBLE „FIREWALL“

With the DUOCAP™ (capsule-in-capsule) technology used for the production of ProCombo, the probiotic and prebiotic are sealed in two capsules that are placed inside each other. Since probiotic microorganisms are extremely sensitive to harmful effects from the environment, they are inserted into the inner capsule. Double encapsulation is a double „firewall“ that protects them from undesirable exposure to oxygen and moisture. Due to that, the number of „good“ bacteria in each capsule remains the same as when it was sealed during the entire shelf life of ProCombo.

1 CAPSULE PER DAY IS ENOUGH

According to expert recommendations, an adult should take between 10 and 20 billion CFU per day in order to achieve the beneficial probiotic effect of Lactobacillus acidophilus. 1 capsule of ProCombo contains 15 billion CFU (or 200 billion CFU/g), which ensures the optimal dose of „good“ bacteria for the balance of the intestinal microflora.

THE SPECIAL GREEN CAPSULE FOR BETTER HEALTH

The Green capsule of ProCombo contains the natural substance chlorophyllin. It is a natural colorant derived from alfalfa, but it is better known for its positive effects on health. It is believed that the intake of chlorophyllin controls the emission of body odors and contributes to intestinal health. Intake of chlorophyllin is a key point in modern guidelines for healthy living.

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RESEARCH

According to the World Health Organization (WHO), the term „probiotic“ can only be used if the bacterial strain has the following characteristics*:

PROVEN ORIGIN

Lactobacillus acidophilus La-14® in ProCombo has been proven as type А1. It is of human origin and is registered by the ATCC (American Type Culture Collection).

SAFETY

Lactobacillus acidophilus has been consumed by humans in yoghurt and other food products for decades now. It has been included in the Inventory of Microorganisms With Documented History of Use in Human Food. The European Food Safety Authority (EFSA) has also included L. acidophilus in the Qualified Presumption of Safety (QPS) list.

RESISTANCE TO THE ACIDIC ENVIRONMENT IN THE STOMACH

EXCELLENT    ++++>90% survival rate in hydrochloric acid and pepsin (1%) at pH3 for 1 hour at 37˚C

RESISTANCE TO BILE SALTS

EXCELLENT    ++++>90% survival rate in medium containing 0.3% bile salts

ATTACHMENT TO MUCUS AND/OR HUMAN EPITHELIAL CELLS AND CELL LINES

The L. acidophilus La-14® strain in ProCombo shows excellent attachment to human epithelial cell lines Saco-2 and HT-29, which leads to rapid colony formation.**

Attachment to human intestinal cells (in vitro)

HT-29: ++++

САСО-2: +++


ABILITY TO REDUCE PATHOGEN ADHESION TO SURFACES

L. acidophilus La-14® in ProCombo shows in vitro inhibition of selected pathogens.**

In vitro inhibition of:

Salmonella typhimurium +++
Staphylococcus aureus ++++
Escherichia coli +
Listeria monocytogenes +

ADDITIONAL QUALITIES of La-14® in ProCombo

RESISTANCE TO ANTIBIOTICS

Studies have shown that the L. acidophilus La-14® probiotic bacteria in ProCombo survive and thrive in the presence of substances (such as antibiotics) that kill other bacteria.**

Evaluation of the resistance to antibiotics of L. acidophilus La-14®

Amoxicillin S
Ampicillin S
Ceftazidime I
Chloramphenicol I
Ciprofloxacin R
Clindamycin I
Cloxacillin S
Dicloxacillin S
Erythromycin S
Gentamicin R
Imipenem R
Kanamycin R
Neomycin R
Nitrofurantoin R
Penicillin G I
Polymixin B R
Rifampicin I
Streptomycin R
Sulfamethoxazole R
Tetracycline R
Trimethoprim R
Vancomycin I

R – Resistant (minimum inhibitory concentration ≥64μg/ml)
I – Intermediate resistant (minimum inhibitory concentration = 8 to 32μg/ml)
S – Susceptible (minimum inhibitory concentration ≤4μg/ml)

IMMUNOMODULATION

A number of studies have shown that L. acidophilus La-14® in ProCombo could modulate immune functions so as to improve the response to oral vaccination, shorten the duration or reduce the risk of certain types of infections, relieve the symptoms or reduce the risk of the development of allergy and other immune-mediated conditions.

The intake of the L. acidophilus La-14® probiotic leads to faster and higher induction of specific lgA and lgG than in the control group, i.e. it stimulates specific immunity.**

Relative change in specific lgG and lgA titre in orally vaccinated humans after supplementation with L. acidophilus La-14®

Maltodextrin
L. acidophilus La-14®

INTAKE
2 placebo capsules (maltodextrin, n=20)
2 capsules x 10⁸ CFU L. acidophilus La-14® (n=9)

*WHO requirements are published in Guidelines for the Evaluation of Probiotics in Food

**Results on the characteristics of L. acidophilus La-14® are published in the "Technical Memorandum of Lactobacillus acidophilus La-14" compiled by Danisco A/S, Brabrand, Denmark

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QUESTIONS AND ANSWERS

What is in ProCombo?

The product ProCombo is a functional combination of an adequate amount of Lactobacillus acidophilus (bacteria that are natural inhabitants of the human body) and special short-chain fructooligosaccharides, which ensure the growth and development of „good“ bacteria. The two ingredients work synergistically and mutually enhance each other’s effect.

What does ProCombo help for?

The Lactobacillus acidophilus bacteria contained in ProCombo contribute to maintaining the balance of the intestinal microflora.

How long should I take ProCombo?

The additional supply of „good“ bacteria, provided by ProCombo, can last between 10 days and 8 weeks without interruption. The intake period is determined by the condition and the goal set. In order to maintain the achieved results, the intake can be repeated after a certain pause. Up to 4 courses of intake of ProCombo are admissible within one calendar year, each of which should have a maximum duration of 8 weeks.

Why does 1 box of ProCombo contain 10 capsules?

The number of capsules is suited for the most common case in which the intake of a probiotic is required – antibiotic treatment. Doctors recommend taking the probiotic for at least 3 more days after the end of the antibiotic therapy, the average duration of which is 7 days. The ten capsules cover the entire required period.

How long does it take to feel the effect of ProCombo?

It is difficult to determine an exact time in which the result of taking ProCombo will be felt, since it depends on the problem. The 10-day intake of ProCombo is only applicable for antibiotic treatment. In all other cases, the continuous intake should last at least 20 days, but not more than 8 weeks. See the answer to the question „How long should I take ProCombo?“

Do I need a prescription for ProCombo?

No, ProCombo is sold without prescription.

Can I take ProCombo more than once a day?

No! The number of bacteria in one ProCombo capsule contains the optimal recommended daily dose for adults.

What is the best time of day to take ProCombo?

ProCombo can be taken at any time of the day.

Should ProCombo be taken before or after meals?

The intake of ProCombo is not related to meals.

Is ProCombo suitable for lactose intolerant individuals?

The product is suitable and even highly recommended in this situation.

Can I open the ProCombo capsule to drink the contents?

Opening the capsule is not desirable, as this deprives you of the effect of the two-stage release.

Should there be an interval between the antibiotic intake and the intake of ProCombo?

It is recommended to take ProCombo at least 2 hours apart from the antibiotic intake, i.e. before or after it.

Can I take ProCombo along with laxatives?

Yes, there is no problem. ProCombo is not a laxative and does not affect the effect laxatives.

Is ProCombo to be kept in a refrigerator?

No, ProCombo is to be stored at room temperature.

Is ProCombo suitable for kids?

ProCombo contains a high number of probiotic bacteria, therefore it is suitable for children over 12 years of age.

Is ProCombo suitable for pregnant and nursing women?

Yes, ProCombo is completely safe and even highly recommended for pregnant and breastfeeding women.

Are there any conditions in case of which ProCombo is not recommended?

The use of ProCombo, as well as probiotic products in general, is not recommended for seriously ill patients in intensive care units, as well as for people with highly compromised immune system. Patients with oncological diseases of the gastrointestinal tract, as well as those who have undergone organ transplantation, should consult a physician.

Is ProCombo suitable in case of irritable bowel syndrome (IBS)?

Yes, supplemental probiotic bacteria intake is highly recommended.

Does ProCombo help in case of constipation?

The probiotic bacteria in ProCombo contribute to proper digestion, which in turn is a key factor in normal bowel motility and regular bowel movements.

Does ProCombo help in case of diarrhea?

The „good“ bacteria in ProCombo „compete” with pathogenic bacteria in the intestines. Thus, they suppress their harmful influence, which is a prerequisite for the normal function of the gastrointestinal tract.

Does ProCombo help in case of gastritis?

The action of probiotic bacteria is in the intestines, which is why they have no direct relevance to the treatment of gastritis.

Can ProCombo be taken in case of colitis?

Yes, it is completely suitable and highly recommended. Gastroenterologists recommend that individuals with colitis take probiotics at least a few times a year.

Does ProCombo help in case of heartburn?

The action of the probiotic bacteria is in the intestines, which is why ProCombo has no direct relation to the occurrence of heartburn in the stomach.

Does ProCombo help in case of reflux?

The action of the probiotic bacteria is in the intestines, which is why ProCombo has no direct relation to the return of stomach contents back into the esophagus (reflux).

Does ProCombo help in case of bloating?

Probiotic bacteria contribute to proper digestion of food, which is why the intake of ProCombo is recommended in case of bloating.

Does ProCombo help in case of intestinal gas?

Probiotic bacteria contribute to the proper digestion of food, which is why ProCombo is recommended for cases of intestinal gas formation.

Does ProCombo help in case of stomach pain?

In case of long-lasting pain in the stomach and/or the abdominal area, it is recommended to consult a physician.

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AWARDS AND RECOGNITION

Most Innovative Product of 2016

Awarded in Italy at the PharmExpo international pharmaceutical exhibition

Most Impressive Probiotic

Awarded in Dubai at the DUPHAT International Pharmaceutical Exhibition